Answer:
B and D
Explanation:
The Black Plague brought about disease EVERYWHERE. Most importantly since it was so contagious, it spread through trade and other human contact. Due to the multitude who died, a lot of those holding a leadership status, leaders were lost, diminishing the power of the empires and nations created. Along with this, trade could not be completed or facilitated with the lack of participation among affected city states.
Kono Dio Da!!!
